9:00am Welcome
9:05-10:00 Keynote Address
Moderator: Kurt Zhang, Texas A&M Univ.
Generative Modeling for Single Cell Genomics: Tools and an Application for Studying How T Cells Develop in the Thymus
Nir Yosef, Univ. of California Berkeley
Session 1: Single Cell in Cancer
Moderator: H. Courtney Hodges, Baylor College of Medicine
10:00-10:25 Generative Modeling for Single Cell Genomics: Tools and an Application for Studying How T Cells Develop in the Thymus
Nicholas Navin, MD Anderson Cancer Center
10:25-10:50 Measuring Cytoskeletal Protein Complex Drug Response Variation by Single-Cell Fractionation
Julea Vlassakis, Rice University
10:50-11:15
Resolved Spatial Transcriptomics of High-Grade Serous Ovarian Carcinoma
Elaine Stur, MD Anderson Cancer Center
11:15-12:00 Vendor Workshop Session
11:15-11:30 Harnessing the Power of full-length Transcriptome Analysis for Biomarker Discoveries
Yanli Liu, Takara Bio
11:30-11:45 Enabling High-Dimensional Biology through Single-Cell Multiomics via the BD Rhapsody™ Platform
Wes Austin, BD Bioscience
11:45-12:00 Fueling the Century of Biology with Single Cell and Spatial Technologies
Spence Fast, 10X Genomics
12:00-1:30 Lunch, Poster session, and vendor booths
12:00-12:20 Rapid Fire Presentations:
Time Resolved Single Cell Transcriptomic Atlas of Neural Crest Cells in Zebrafish Reveals Lineage-Specific Hox Transcriptional Code
Adam Howard, Rice Univ. Poster 5
Tumor and TME Metabolic Reaction Flux Framework from Bulk and Single Cell Gene Expression Data
Yuefan Huang, Univ. of Texas Health Science Center Houston Poster 6
Single-nucleus RNA Sequencing Reveals the Doxorubicin-Induced Cognitive Impairment Reversal by HDAC6 Inhibition
Rajasekaran Mahalingam, MD Anderson Cancer Center Poster 12
Inquiries at Super-Resolution: Is Genome Organization a Platform for Gene Regulation?
Guy Nir, Univ. of Texas Medical Branch at Galveston Poster 13
12:00-12:50 Vendor booths/breakout rooms
12:20-12:50 Lunch
12:50-1:30 Poster Session
1:30-2:15 Keynote Address
Moderator: Peter McCaffrey, Univ. of Texas Medical Branch at Galveston
Talk title tba
Matt Spitzer, UCSF & Teiko Bio
Session 2: Software Tools and Technologies
Moderator: Ken Chen, MD Anderson Cancer Center
2:20-2:45 Single Cell Spatial Atlas of the Retina
Rui Chen, Baylor College of Medicine
2:45-3:10 Spatial Charting of Single Cell Transcriptomes in Tissues
Runmin Wei, MD Anderson Cancer Center
3:10-3:35 scTenifoldXct: Semi-supervised Manifold Alignment for Inference of Cellular Interactions Through Construction of Intra- and Intercellular Gene Signaling Networks
Yongjian Yang, Texas A&M Univ.
Session 3: Single Cell Genomics Applications
Moderator: Peter McCaffrey, Univ. of Texas Medical Branch at Galveston
3:35-4:00 Single Cell RNA-seq and Mass Cytometry Reveals a Novel and a Targetable Population of Macrophages in Idiopathic Pulmonary Fibrosis
Ivan Rosas, Baylor College of Medicine
4:00-4:25 Single-cell Manifold-preserving Feature Selection for Detecting Rare Cell Populations
Shaoheng Liang, MD Anderson Cancer Center
4:25-4:50 Time-lapse Imaging Microscopy in Nanowell Grids (TIMING™): A Platform to Expand Multi-Dimensional Profiling of Single Cells
Mohsen Fathi, CellChorus
4:50 Closing Remarks